It is known that rapid weight loss can lead to gallstones, including in people that have been on severe diets - without the use of jabs.
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Nature, Published online: 25 February 2026; doi:10.1038/d41586-026-00292-7
Starring: Alan Cumming, Mark Ballas, Maura Higgins, Tara Lipinski, Eric Nam, Rob Rausch, and Johnny Weir